An international study had revealed new insight into tau protein and its binding.
The tau protein is an important factor linked to the development of human neurodegenerative diseases,
which also includes disease like Alzheimer’s and others.
We still do not know much about tau and other similar proteins.
These discoveries has come from the work of an international team at Charles University, Prague.
The study has been published in Nature Chemical Biology.
It shows how tau protein can form coatings or envelopes on cytoskeletal structures of the cell called microtubules.
It subsequently changes the properties of the coated microtubules and also prevent the passage of certain
molecular motors that provide intracellular transport just by moving along the microtubules.
The proteins that bind to microtubules are collectively referred to as MAPs.